Long-term deep spots on both sides of the nose are often due to acne scars, pigmentation, or enlarged pores. You can use a gentle face wash, apply sunscreen daily, and try creams with ingredients like niacinamide, vitamin C, or retinoids to gradually improve the skin. Avoid picking or squeezing the area. If the spots are stubborn, a dermatologist may suggest treatments like chemical peels or laser therapy for better results.