Fungal infections with itching are usually caused by sweat and moisture, which allow the fungus to grow on the skin. A doctor may prescribe an antifungal cream to help stop the infection and reduce itching. Apply a thin layer to clean, dry skin once or twice daily as advised, and continue the full course even if it looks better. Keep the area dry, wear loose cotton clothes, and avoid scratching. Talk to your doctor if it does not improve.