A G6PD level of 18.6 is normal and not deficient, which is excellent news. The primary concern with dapsone is in individuals with G6PD deficiency (low levels), which can lead to red blood cell breakdown. Since her G6PD levels are healthy, dapsone is generally safe for her to take from this standpoint. However, because she is 75, please ensure her doctor reviews her complete health profile and current medications before she starts.

The white patches in your mouth could be oral thrush, which can sometimes occur with certain medications, or another manageable condition. Please have a healthcare provider examine your mouth to provide an accurate diagnosis and appropriate treatment, such as a mild antifungal rinse. For your diet, try to focus on soft, non-acidic, and non-spicy foods to prevent irritating your mouth. Staying well-hydrated and practicing gentle oral hygiene will also provide comfort.

Missing a small portion of a single clofazimine dose will not affect your father's leprosy treatment. Clofazimine builds up and stays in the body for a very long time, so a one-time partial dose is not a concern, especially since he successfully took his other daily medications (rifampicin, clofazimine, and dapsone). You do not need to give him an extra dose to make up for the spilled amount. Simply continue with his regular, prescribed daily dosing schedule tomorrow.

Yes, a non-itchy rash on your arms could potentially be a reaction to your acne medications, dapsone or Acnesia, especially if applied directly to that area or taken orally. Sometimes, these treatments can cause mild skin irritation or a localized sensitivity reaction. Please be reassured that this is often manageable. I suggest temporarily stopping the application of these products on your arms and consulting your doctor or dermatologist. They can gently evaluate your skin, determine the exact cause, and safely adjust your treatment plan to keep your skin clear and comfortable.

A bacterial level of 4+ indicates Multibacillary leprosy, which requires immediate, specialized treatment. The standard treatment recommended by the WHO is Multidrug Therapy (MDT), which consists of a combination of three medicines: Rifampicin, Dapsone, and Clofazimine, typically taken for 12 months. Since you have seen no relief in two years, it is critical that you consult a dermatologist or leprologist immediately. You need to be evaluated for drug resistance or leprosy reactions. Please do not self-medicate, as strict adherence to a supervised regimen is essential to cure the infection and prevent permanent nerve damage.

Since your current regimen includes multiple oral antibiotics and topical treatments like benzoyl peroxide, adapalene, clindamycin, and dapsone, your skin may be overwhelmed and irritated, which can worsen inflammation. Deep, cystic acne linked to hormonal conditions like PCODs often resists standard antibiotics. I highly recommend consulting your dermatologist to re-evaluate. They may suggest simplifying your routine to heal your skin barrier, confirming your PCOD diagnosis, or discussing stronger targeted options like oral isotretinoin or specific hormonal therapies.