Since you are of normal weight, long-term management focuses on gentle lifestyle measures like a balanced, low-glycemic diet and strength training to maintain insulin sensitivity. While medroxyprogesterone (Deviry) is excellent for protecting your uterine lining by inducing regular bleeds, your doctor may discuss long-term options like generic oral contraceptive pills or generic metformin to help regulate your cycles naturally. Managing stress and getting quality sleep also play a huge role. You are doing great, and with regular follow-ups with your gynecologist.

It is completely understandable to feel concerned, but please try not to worry. After finishing a course of Deviry (medroxyprogesterone acetate), it is quite common for your period to take up to 10 to 14 days to start, so waiting a few more days is perfectly safe. Since your home pregnancy tests are negative, pregnancy is highly unlikely. Stress, hormonal fluctuations, or the underlying reason you were prescribed the medication can also delay your bleed. If your period does not arrive within another week, please reach out to your gynecologist. They can evaluate your hormone levels and guide you on the next steps.

Deviry (medroxyprogesterone) is prescribed to help restart your period, but sometimes a withdrawal bleed doesn't happen if your estrogen levels are low or if the uterine lining is quite thin. Other factors, such as stress, thyroid changes, or hormonal imbalances, can also delay your cycle. Since it has been two months, the best next step is to consult your gynecologist. They can run simple hormone tests or perform an ultrasound to find the exact cause and safely guide your next steps.

While both medications are helpful, taking Deviry (medroxyprogesterone) and Trenexa (tranexamic acid) together can increase the risk of blood clots. More importantly, Trenexa is meant for heavy menstrual bleeding, not for bleeding from your bottom (rectal bleeding). Rectal bleeding can be caused by various issues like hemorrhoids or small tears, and it requires a proper medical evaluation rather than self-treatment. I gently advise against taking Trenexa for this bleeding. Please consult your doctor so they can safely examine you, find the exact cause of the bleeding, and prescribe the right treatment.

A missed period for 40 days with a negative pregnancy test is often due to a hormonal imbalance, which can be triggered by stress, weight changes, excessive exercise, or conditions like Polycystic Ovary Syndrome or thyroid problems. In many cases, it is not serious, but it should be evaluated if it happens repeatedly. Treatment depends on the cause. Your doctor may advise lifestyle changes (healthy diet, regular exercise, stress management), check hormone levels, and sometimes prescribe medicines like progesterone (e.g., Deviry) to help induce a period. It is also a good idea to repeat the pregnancy test if there was any recent risk, or get a blood test for confirmation. If your cycles continue to be irregular or absent, a proper medical evaluation is important to ensure the right treatment and prevent long-term issues.

Since your thyroid is normal, it is safest to wait another week and repeat the home pregnancy test using your first morning urine, as ovulation might have occurred later than usual. You should avoid taking Deviry (medroxyprogesterone acetate) until you have confirmed with your healthcare provider that you are definitely not pregnant. Medroxyprogesterone acetate is used to induce a period, but ruling out pregnancy first is essential.