After finishing a course of Deviry (medroxyprogesterone acetate), a withdrawal bleed typically starts within 3 to 7 days, but it can sometimes take up to 14 days. Since it has been ten days, this delay can still be normal. I suggest waiting a few more days. If there is any chance of pregnancy, taking a home pregnancy test is a good next step. If your period does not arrive after 14 days, please contact your doctor to discuss the next steps.

After finishing Deviry (medroxyprogesterone), it typically takes 3 to 10 days?and sometimes up to two weeks?for withdrawal bleeding to begin. Since your pregnancy tests are negative, you can feel reassured. The breast pinching and mild lower body discomfort you are experiencing are very common side effects of hormonal fluctuations as the medication leaves your body, particularly with PCOS. Try to stay relaxed, and if your period doesn't start within 10 to 14 days, or if the pain becomes severe, please contact your doctor.

Deviry (medroxyprogesterone acetate) helps regulate your cycle, and withdrawal bleeding typically starts 3 to 10 days after completing the entire medication course. Since there was no ejaculation, the chance of pregnancy is very low, though pre-ejaculatory fluid carries a minor risk. Your underlying PCOS can also contribute to the delay. I recommend waiting up to 10 days after finishing your Deviry dose. If your period still does not arrive, taking a home pregnancy test will help provide peace of mind.

Since the initial trial didn't induce menstruation, the next step is typically to check your hormone levels (like estrogen, thyroid, and prolactin) and perform an ultrasound to check your uterine lining. Your doctor may then suggest a combined estrogen and progesterone cycle to help prime your lining and encourage a bleed, or further investigate underlying conditions like PCOS. Please schedule a follow-up with your gynecologist.

While pregnancy is a possibility and should be ruled out first with a simple home pregnancy test, there are other common reasons for not bleeding. With PCOS, your estrogen levels might be too low to build up the uterine lining, meaning there isn't enough to shed even after taking Deviry (medroxyprogesterone acetate). Please take a pregnancy test to be sure. If it is negative, I recommend reaching out to your doctor, who can help evaluate your hormone levels and guide your next steps.

While Deviry (medroxyprogesterone) is helpful for inducing a temporary period, it does not cure the underlying cause of your irregular cycles. Since the delay has returned, it is important to visit a gynecologist to find out why this is happening. They may suggest simple hormone tests or an ultrasound to check for common, highly manageable conditions like Polycystic Ovary Syndrome (PCOS) or thyroid imbalances. Please rest assured that this is a very common issue with many effective, long-term solutions. You're doing the right thing by seeking answers, and with proper guidance, we can help regulate your cycle comfortably.