Using Dexona (dexamethasone) and Avil (pheniramine) for a long period like 5 years is not considered safe without close medical supervision, especially because Dexona is a steroid that can cause serious side effects over time such as weight gain, diabetes, high blood pressure, weak bones (osteoporosis), increased infection risk, and hormonal imbalance; Avil, being an antihistamine, may cause drowsiness, dry mouth, and reduced alertness with long-term use. While these medicines do not directly damage the kidneys in most cases, long-term steroid use can indirectly affect overall health and may worsen existing conditions. It is very important not to stop Dexona suddenly, as this can cause withdrawal problems; instead, you should consult a doctor to gradually reduce and stop it safely and to find a better long-term treatment for your underlying condition.

Indeed, prolonged VM (stress or steroid-related) hyperglycemia can be dangerous since it raises the risk of infections and consequences from diabetes, so it must be monitored and controlled. Weight gain, elevated blood sugar, acidity, and mood swings are among the adverse effects of dexona (dexamethasone), particularly when used repeatedly or over an extended period of time.