Your new symptoms of irritability and anger could indeed be linked to your medications or how they interact. Long-term use of sedatives like nitrazepam and etizolam can sometimes cause paradoxical reactions, leading to unexpected aggression or mood changes. Additionally, combining these with risperidone, divalproex, and neuropathy medications can affect brain chemistry or cause metabolic fluctuations (like blood sugar shifts) that impact mood. Please do not stop any medication abruptly, as this can be dangerous. Instead, consult your prescribing doctor immediately. They can safely evaluate your drug levels, check your blood sugar, and carefully taper or adjust your therapy to restore your emotional balance.