Sometimes, the abnormal electrical pathways are located deep within the heart tissue or in areas that are technically difficult to reach. Please be reassured that a repeat ablation, sometimes using a different mapping technology or cold therapy (cryoablation), is often highly successful as a permanent solution. While you discuss these options with your electrophysiologist, continuing your prescribed diltiazem (Dilzem) and bisoprolol (Concor Cor) is very important to keep your heart rate safely controlled and keep you feeling comfortable.