Thyroxine is the standard medicine used to replace thyroid hormone and should be taken regularly in the dose prescribed by your doctor. It is important not to change the dose on your own. Thyrogrit is an Ayurvedic supplement that contains herbal ingredients such as Guggulu, Trikatu, Pippal, Dhaniya, and Singhada, which are sometimes used for general thyroid support and wellness. However, its effectiveness and safety can vary from person to person, and it should not replace prescribed thyroxine. The stretching or tightness in your hands and legs may be related to a thyroid imbalance, muscle strain, or perimenopausal changes. Since your symptoms improve with your current medicines, it is important to continue only under medical supervision. You should consult your doctor to review your thyroid levels and overall hormonal status. Your doctor can decide whether you need to continue Thyrogrit or adjust your thyroxine dose for better long-term management.