During early pregnancy, safety is the top priority. For vomiting, Pyridoxine (Vitamin B6) and Doxylamine are safe, first-line options. For loose motions, staying hydrated is crucial; Oral Rehydration Salts (ORS) are completely safe and highly recommended. Avoid self-medicating with standard over-the-counter anti-diarrheal tablets (like loperamide) or antibiotics without medical advice. If symptoms are severe, your doctor can safely prescribe specific antiemetics like metoclopramide or ondansetron. Always consult your obstetrician before taking any medication to ensure it is safe for you and your baby.