Severe nerve pain extending from the brain to the foot, especially worsening during night shifts, suggests a condition that needs careful evaluation and management. This type of pain could be related to neuropathic causes, which sometimes respond to specific medications like duloxetine, an antidepressant also used to treat nerve pain.

• You should consult a neurologist or pain specialist promptly to get a thorough assessment and appropriate diagnosis.
• Medications such as duloxetine (found in products like Duzela 30 Capsule) may be prescribed to help manage neuropathic pain, but only under medical supervision.
• Avoid self-medicating and inform your doctor about all symptoms, including timing and triggers like night shifts.
• Keep a pain diary noting intensity, duration, and any associated symptoms to help your doctor tailor treatment.
• If you experience worsening symptoms such as weakness, loss of sensation, or bladder/bowel issues, seek emergency care immediately.

Please see a neurologist soon to discuss your symptoms and get a personalized treatment plan. If the pain is severe or accompanied by new neurological signs, do not delay seeking urgent medical attention.To narrow down potential causes, we will need some more information.I understand you're having severe nerve pain from your brain to your right foot, especially when working nights. To better assist you, could you please share your age and gender?