I have been taking Tendia 20 for high blood sugar and Eltroxin 50mcg for high TSH while trying to conceive. Although my levels initially normalised, two rounds of Materna HCG injections (5k and 10k) failed to help me conceive, and my TSH level has now drastically spiked to 60. Why did my TSH level increase so much despite the medication, and what medications or treatment plan should I follow now to successfully conceive?

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I have been taking Tendia 20 for high blood sugar and Eltroxin 50mcg for high TSH while trying to conceive. Although my levels initially normalised, two rounds of Materna HCG injections (5k and 10k) failed to help me conceive, and my TSH level has now drastically spiked to 60. Why did my TSH level increase so much despite the medication, and what medications or treatment plan should I follow now to successfully conceive?

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I have been taking Tendia 20 for high blood sugar and Eltroxin 50mcg for high TSH while trying to conceive. Although my levels initially normalised, two rounds of Materna HCG injections (5k and 10k) failed to help me conceive, and my TSH level has now drastically spiked to 60. Why did my TSH level increase so much despite the medication, and what medications or treatment plan should I follow now to successfully conceive?

Asked by Female, 30 · 10 days ago

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

10 days ago

Your TSH spiked because fertility treatments (like HCG) raise estrogen levels, which drastically increase your body's thyroid hormone requirement. Your current Eltroxin 50mcg dose is now insufficient. High TSH directly impairs ovulation and prevents conception. Recommended Plan: 1. Adjust Eltroxin: Consult your doctor immediately to increase your Eltroxin dose, aiming for a TSH below 2.5 mIU/L. 2. Review Diabetes Meds: Discuss switching Tendia (teneligliptin) to pregnancy-safe alternatives like Metformin or insulin. 3. Pause Fertility Treatments: Hold HCG injections until thyroid levels stabilise. Once TSH and blood sugars normalise, your chances of successful conception will improve significantly.

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I have been taking Tendia 20 for high blood sugar and Eltroxin 50mcg for high TSH while trying to conceive. Although my levels initially normalised, two rounds of Materna HCG injections (5k and 10k) failed to help me conceive, and my TSH level has now drastically spiked to 60. Why did my TSH level increase so much despite the medication, and what medications or treatment plan should I follow now to successfully conceive?

Answered 10 days ago