Depression after a stroke or paralysis is very common and highly treatable. However, because of your medical history, antidepressant medications must be carefully selected to avoid dangerous interactions with other drugs you may be taking, such as blood thinners. Doctors often prescribe Selective Serotonin Reuptake Inhibitors (SSRIs) like Escitalopram or Sertraline, but you should never self-medicate. Please consult your neurologist or a psychiatrist. They will evaluate your health and safely prescribe the right medication and dosage for you. Combining medication with therapy often yields the best results.