Esomac L contains levosulpiride, which can increase prolactin levels in the body. This hormonal change is a known and common cause of missed or irregular periods. Regarding pregnancy, while home tests are generally reliable, a false negative can occur if the test was taken too early. I recommend waiting a few days to retest using first-morning urine, or consulting her doctor for a simple blood pregnancy test and to discuss her medication. Please be reassured that this is a manageable situation, and her doctor will safely guide you both.