Reduced sexual sensation and difficulty with ejaculation in your case are most likely due to a combination of medications and underlying health conditions. Drugs like Metocard XL (a beta-blocker) and Depran (an antidepressant) are known to cause sexual side effects such as reduced desire, delayed ejaculation, or decreased pleasure. High blood pressure itself can also affect blood flow and nerve function, which plays an important role in sexual performance. The best approach is to consult your doctor before making any changes. They may adjust the dose, switch to alternative medicines with fewer sexual side effects, or suggest treatments specifically for sexual dysfunction if needed. Lifestyle measures like regular exercise, stress reduction, good sleep, and avoiding alcohol or smoking can also improve sexual health. Open communication with your partner is equally important. In most cases, once the cause is addressed, sexual function improves gradually.