While there are no medications specifically approved to cure personality disorders, several medicines can effectively help manage your symptoms. Doctors often prescribe: Antidepressants (such as sertraline or fluoxetine) to ease depression, anxiety, or anger; Mood stabilisers (such as lamotrigine) to reduce mood swings and impulsivity; and low-dose Antipsychotics (such as aripiprazole) to help with severe anxiety or distorted thinking. These medications work best when combined with psychotherapy, like talk therapy, which is the primary treatment. Your doctor will carefully tailor a plan to support your well-being.