Since your current dose of leflunomide (Rumalef) isn't fully controlling the inflammation, your rheumatologist has several excellent options. They may consider safely increasing your leflunomide dose, combining it with hydroxychloroquine, or transitioning you to biologic DMARDs or JAK inhibitors, which are highly effective at targeting stubborn inflammation. Because your liver is doing so well, you have many safe pathways forward. Please share these results with your specialist soon so they can adjust your plan and help you find relief.

Stomach discomfort is a common side effect of methotrexate (Folitrax). To help manage this, doctors often prescribe folic acid or adjust the dosing schedule. However, because new stomach and back pain should be carefully evaluated, it is very important that you contact your prescribing doctor before taking your next dose. They can safely assess these symptoms and adjust your treatment plan if needed. For now, try to stay well-hydrated and rest.

The medications you are taking?Folitrax-25 (methotrexate), HCQS-200 (hydroxychloroquine), and HSCAL-D3 (calcium/vitamin D3)?are typically prescribed for autoimmune conditions like rheumatoid arthritis. While these conditions are chronic and not completely curable, they are highly manageable. The main goal of your treatment is to achieve remission, which keeps you pain-free and protects your joints from damage. Because of this, you will likely need to continue these medications long-term. Please be reassured that with consistent treatment, most young adults lead very active, healthy, and fulfilling lives.