Switching from dapagliflozin 10 mg to linagliptin 5 mg is safe, but must only be done under your doctor's supervision. These medications belong to different drug classes and lower blood sugar differently. Dapagliflozin helps your kidneys remove excess sugar through urine, while linagliptin helps your body release more insulin when needed. Because they have different effects on your body, heart, and kidneys, a direct switch requires your doctor to evaluate your blood sugar control and overall health first. Please consult your prescribing doctor before making any changes to your medication routine.