Pain during urination is most commonly caused by a urinary tract infection (UTI). To treat it effectively, you need to see a healthcare provider for a quick urine test, as a specific course of prescribed antibiotics (such as Nitrofurantoin or Fosfomycin) is usually required. Please avoid taking leftover antibiotics. For immediate, temporary relief from the burning sensation, you can take over-the-counter Phenazopyridine and drink plenty of water to help flush out your system. If you develop a fever or back pain, seek medical attention immediately.