Taking Glimestar PM1 twice a day in well-controlled diabetes usually does not cause significant weight gain for most people, as it primarily helps regulate blood sugar. Maintaining a healthy diet and regular exercise is important. You should consult your doctor if you notice unusual weight changes.

Long-term use of Glimestar PM1 is generally safe if your blood sugar is well controlled and you are regularly monitored. Periodic check-ups are important for assessing kidney and liver health and overall health. You should consult your doctor to review your treatment and ensure it remains appropriate.