I'm sorry to hear you're experiencing throat irritation, cough, and nasal blockage at night. These symptoms can be quite uncomfortable.

Since you are using Otrivin drops (a nasal decongestant) and Ambrolite D syrup (which contains an antihistamine, decongestant, and cough suppressant), here are some additional tips that may help relieve your symptoms:

• Maintain hydration: Drink plenty of warm fluids like herbal teas or warm water with honey and lemon to soothe your throat and help loosen mucus.
• Use a humidifier: Adding moisture to the air in your bedroom can ease nasal congestion and throat irritation.
• Elevate your head while sleeping: Using an extra pillow can help reduce nasal blockage by improving drainage.
• Avoid irritants: Stay away from smoke, strong perfumes, or dust that can worsen your symptoms.
• Limit use of nasal drops: Otrivin drops should not be used for more than 3 consecutive days to avoid rebound congestion.

If your symptoms persist beyond a week, worsen, or if you develop fever, difficulty breathing, or severe pain, please consult an ear, nose, and throat (ENT) specialist for a thorough evaluation and appropriate treatment.

Remember, while Ambrolite D syrup helps with dry cough and nasal congestion, it is important to follow the prescribed dosage and inform your doctor if you have any other medical conditions or are taking other medications.To narrow down potential causes, we will need some more information.Please tell me your age and gender.