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  5. I finished taking Percin (Prulifloxacin) 3 days ago, and now my doctor has prescribed Augmed 625 (Amoxicillin + Clavulanic acid). Can I start this new antibiotic, and will there be any side effects?

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I finished taking Percin (Prulifloxacin) 3 days ago, and now my doctor has prescribed Augmed 625 (Amoxicillin + Clavulanic acid). Can I start this new antibiotic, and will there be any side effects?

Asked by Female, 44 · 3 months ago

If Augmentin 625 (Amoxicillin + Clavulanic acid) is prescribed shortly after completing Percin (Prulifloxacin 600 mg), it may be a medically appropriate switch based on updated findings such as culture results or poor response to the initial antibiotic, and while this transition is generally safe under medical supervision, mild side effects like stomach upset may occur. However, if Percin was taken without a doctor’s guidance and not disclosed during consultation, it could lead to inappropriate treatment, increased risk of side effects or resistance, and reduced effectiveness, because current medical reports may show the present condition but not recent antibiotic exposure, making full disclosure of all medications essential for safe and effective care.
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It's understandable to wonder about starting Augmentin soon after finishing Percin, so let's clarify that for you.

  • Safety of Taking Augmentin After Percin:
    Generally, starting Augmentin (amoxicillin-clavulanate) shortly after completing a course of Percin (prulifloxacin), which is a fluoroquinolone antibiotic, is considered safe. These antibiotics belong to different classes and work differently. However, it’s important to follow your doctor’s advice closely, especially regarding why the switch was made, to ensure the treatment is appropriate for your infection.

  • Potential Side Effects:

    • Augmentin commonly may cause gastrointestinal upset such as nausea, diarrhea, skin rash, or yeast infections.
    • Percin can cause stomach pain, rash, muscle pain, or respiratory symptoms. Since you recently completed Percin, be mindful of any lingering side effects.
    • Overlapping side effects are uncommon but watch for any new or worsening symptoms.
  • Drug Interactions and Precautions:
    There are no significant direct interactions between prulifloxacin and Augmentin. Still, monitor for any unusual symptoms like severe rash, difficulty breathing, or persistent diarrhea, which could indicate adverse reactions.

  • When to Contact Your Doctor:
    Seek immediate medical attention if you experience signs of an allergic reaction such as swelling, hives, difficulty breathing, or severe skin reactions. Also, report any unusual or severe side effects promptly.

  • Additional Recommendations:
    Take Augmentin with meals to reduce stomach upset and complete the full prescribed course even if you start feeling better. This helps prevent antibiotic resistance and ensures infection clearance.

  • Relevant Medical Specialties:
    Infectious disease specialists or your general practitioner can best guide antibiotic management and monitor your response.

  • Diagnostic or Monitoring Advice:
    Follow-up may be needed if symptoms persist or worsen, and your doctor might order tests to assess infection status or side effects.

If you have any concerns or experience symptoms, please consult your doctor promptly for personalized advice.

Answered 3 months ago