1. Duration of Treatment: Antidepressants like Bupron XL 150 mg are typically taken for 6 to 12 months after symptoms improve to prevent relapse.

2. Individual Response: The duration depends on your response to the medication and symptom recurrence upon stopping.

3. Medical Supervision: Regular follow-ups with your healthcare provider are crucial to assess progress and decide on tapering or stopping the medication safely.

4. Managing IBS: While primarily for depression and anxiety, your doctor will monitor its effect on IBS symptoms.

Recommendation: Always consult your doctor before making any changes to your medication regimen.