Cefrine Syrup contains Cefdinir, a cephalosporin antibiotic used to treat bacterial infections. It is not known to cause fever immediately after administration. The fever is likely a result of the illness itself, rather than a reaction to the antibiotic. Administering paracetamol to reduce fever is a safe and common practice, as advised by your doctor. Unless your doctor advises otherwise, you should complete the full course of antibiotics to effectively treat the infection and prevent the development of resistance. If your child develops a rash, swelling, difficulty breathing, or appears unwell, seek medical attention immediately. For any concerns about fever or medication, it’s best to consult your paediatrician.