Feeling nauseous after taking Glycomet Trio Forte (glimepiride, metformin, and voglibose) is a common side effect, especially when starting the medication. To reduce nausea, take the tablet with food, drink plenty of water, and avoid lying down immediately after taking it. Do not take anti-vomiting medicine on your own without consulting your doctor, as some may interact with your diabetes medications. If nausea is severe, persistent, or accompanied by other symptoms, contact your doctor promptly.