Using Otrivin saline nasal spray daily before sleeping is generally safe for most people. This spray helps to moisturize and clear nasal passages without the risk of dependency that some medicated sprays have. However, it's important to use it as directed on the package or by your healthcare provider.

If you have any ongoing nasal issues or allergies, or if you notice irritation or worsening symptoms, it would be best to consult a doctor. Also, if you are considering using other nasal sprays alongside Otrivin, especially decongestant sprays, be cautious as those should not be used daily for extended periods.

In summary:

• Otrivin saline nasal spray is safe for regular use to keep nasal passages moist.
• Avoid using medicated nasal sprays daily for more than a few days without medical advice.
• Consult your healthcare provider if symptoms persist or worsen.

If you have any specific health conditions or concerns, please share them for more personalized advice.