Palip XR 6 mg and Palido OD 6 mg both contain paliperidone, but they may differ in brand formulation and the specific extended‑release technology used. Even slight differences in extended‑release medicines can affect symptom control and side effects, especially in bipolar disorder, where long‑term stability is essential. Inactive components can also affect how the drug is absorbed and eliminated, potentially altering its overall effect. Therefore, switching should not be done without medical guidance. Please consult the prescribing doctor, who can assess the situation and recommend the most appropriate option.