It sounds like you're noticing a change in the texture of your Sucral Ano cream after switching from an aluminum to a plastic tube, and that's understandably concerning.

• Why consistency changes: Topical creams like Sucral Ano can change texture after opening due to exposure to air, temperature fluctuations, and the packaging material. Air can cause some ingredients to separate or evaporate, altering the cream’s feel.

• Impact of packaging change: Aluminum tubes provide a better barrier against air and moisture compared to plastic tubes. Switching to plastic may allow more air or moisture interaction, which can cause the cream to become more liquid over time.

• Storage advice: To help maintain the cream’s consistency, store it in a cool, dry place away from direct sunlight and heat. Always close the tube tightly after use to minimize air exposure.

• Safety and effectiveness: Despite the change in texture, the medication should still be effective and safe to use as long as it is within its expiry date and stored properly. However, if you notice any unusual smell, color change, or irritation after application, it’s best to stop using it and consult a dermatologist or a specialist doctor.

If you remain concerned about the change or its effects, discussing this with your prescribing doctor can provide reassurance and guidance tailored to your situation.