It sounds like your thigh pain after doing 160 squats is quite severe and is affecting your daily activities and sleep, which suggests significant muscle strain or injury.

• Apply cold packs to your thighs for the first 24-48 hours after exercise to reduce inflammation, then switch to warm compresses to relax muscles.
• Rest and avoid strenuous activity until the pain improves.
• Over-the-counter pain relievers like ibuprofen can help reduce pain and inflammation, but consult a doctor before starting any medication.
• Gentle stretching and light movement may help prevent stiffness once acute pain lessens.
• If pain persists beyond a few more days, worsens, or you notice swelling, numbness, or weakness, see an orthopedic specialist promptly.

Since your pain is intense and interfering with basic movements and sleep, I recommend consulting an orthopedic doctor soon to rule out any serious muscle injury or complications and to get appropriate treatment. If the pain suddenly worsens or you develop other symptoms like fever or inability to move the leg, seek emergency care immediately.To narrow down potential causes, we will need some more information.I understand you're experiencing significant thigh pain after doing squats. To provide the best advice, could you please share your age and gender?