I'm sorry to hear you're experiencing sudden discomfort, sleeplessness, anxiety, and thoughts of self-harm. These symptoms can be very distressing and require prompt attention.

• Please reach out immediately to a mental health specialist such as a psychiatrist or clinical psychologist for urgent evaluation and support.
• If you feel you might harm yourself, do not hesitate to contact emergency services or go to the nearest emergency room right away.
• Avoid alcohol or any substances that might worsen your symptoms.
• Try to stay in a safe environment and share your feelings with a trusted person who can support you.
• If you are currently on medications like Venlafaxine (an antidepressant), inform your doctor about these symptoms as they may need to adjust your treatment.

Your safety is the priority, so please seek professional help without delay. If you want, I can explain more about managing anxiety and sleep difficulties.To narrow down potential causes, we will need some more information.Please tell me your age and gender.