I'm sorry to hear that you've been dealing with persistent mouth ulcers for such a long time. Mouth ulcers affecting the mouth, throat, and tongue for six years can be quite distressing.

Vitcofol Injection, which contains folic acid, vitamin B12 (cyanocobalamin), and nicotinamide (vitamin B3), is used to treat nutritional deficiencies and may have helped by addressing underlying vitamin deficiencies. However, since the ulcers have returned after five years of relief, it suggests that there might be other contributing factors or a need for reassessment.

Here are some important points to consider:

• Chronic mouth ulcers can be caused by various factors including nutritional deficiencies, infections, autoimmune conditions, allergies, or other systemic illnesses.
• It is important to have a thorough evaluation by a specialist, such as an oral medicine specialist or an otolaryngologist (ear, nose, and throat doctor), to identify any underlying causes.
• Additional tests might be needed to check for deficiencies, infections, or immune-related conditions.
• Maintaining good oral hygiene, avoiding irritants (like spicy or acidic foods), and managing stress can help reduce ulcer recurrence.
• Since Vitcofol Injection is prescription-based, any further use or alternative treatments should be guided by a doctor.

I strongly recommend consulting a specialist doctor who can perform a detailed assessment and tailor a treatment plan specific to your condition. If symptoms worsen or you experience difficulty swallowing or severe pain, seek medical attention promptly.To narrow down potential causes, we will need some more information.Please tell me your age and gender. I understand you've been dealing with mouth ulcers for a while, and the previous treatment isn't working anymore. I will do my best to assist you.