Dark spots all over your hands for many years may be due to pigmentation issues, sun damage, or chronic skin conditions. Simple creams alone usually won't clear long-standing spots. You should consult a dermatologist for proper evaluation; they may suggest topical treatments, chemical peels, laser therapy, or professional skin care. Meanwhile, use sunscreen on your hands daily, avoid harsh soaps, and keep your skin moisturised to prevent further darkening.

HHLite cream can help reduce pigmentation, but it usually takes several weeks (often 4 to 8 weeks) to see results. Use it exactly as directed by your doctor and do not apply more than recommended, as overuse can irritate the skin. Always protect your skin from sun exposure while using the cream.