Caution is required with this combination. Himract contains Hypericum perforatum (St John's-wort), which is known to interact with many antidepressants. Taking it along with Peroxitene 25 mg may increase the risk of serotonin syndrome, a potentially serious condition caused by excess serotonin levels. It can also affect how the antidepressant works in the body. Because of this, the combination is generally not recommended without medical supervision. You should consult your doctor before using them together so they can assess safety and suggest a more appropriate option if needed.