Yellowing of the eyes (jaundice) is common in sickle cell anaemia, caused by the rapid breakdown of fragile red blood cells, which releases a yellow pigment called bilirubin. To manage this, doctors often prescribe hydroxyurea, which helps reduce cell breakdown and painful crises. Daily folic acid supplements are also used to support new, healthy red blood cell production. Staying exceptionally well-hydrated with fluids is crucial to help your body flush out bilirubin. While this symptom is manageable, please consult your haematologist soon. They can run simple tests to check your liver and gallbladder, ensuring your treatment is safely adjusted.