For severe tooth pain, you can take a simple and generally safe pain reliever like paracetamol or ibuprofen if you do not have stomach problems, kidney disease, or allergies and have taken it safely before; these can help reduce pain temporarily, but they will not treat the underlying cause. Avoid taking multiple painkillers together or exceeding the recommended dose, and do not rely on strong combinations without medical advice. You can also rinse your mouth with warm salt water and avoid chewing on the painful side for some relief. However, since severe tooth pain usually indicates an issue like infection or decay, it is very important to see a dentist as soon as possible for proper treatment. Seek urgent care if you develop swelling, fever, or difficulty opening your mouth.