I understand how frustrating dark spots can be, but since you are taking Isotroin (isotretinoin), your skin is currently very sensitive and fragile. Strong, fast-acting treatments can cause irritation and actually worsen hyperpigmentation. Obril First contains gentler ingredients, which naturally take longer to work. While on isotretinoin, it is safest to use mild, soothing ingredients like niacinamide or azelaic acid, and absolutely essential to apply a broad-spectrum sunscreen daily, as UV rays darken these spots. Please consult your dermatologist before adding any new creams, as protecting your skin barrier is the priority right now.

As these symptoms have not cleared with antibiotics like ciprofloxacin, Augmentin, and azithromycin, or with Isotroin, I highly recommend consulting a dermatologist first. A dermatologist specializes in deep skin infections, severe cystic acne, and managing Isotroin therapy. They can properly diagnose the root cause and adjust your treatment. If they suspect the swelling originates deeper, such as in the salivary glands, they will coordinate with an ENT specialist. Please don't worry; seeing a dermatologist is the best next step to getting you the right relief.

Isotroin works best when taken with or after a meal, especially one containing a little healthy fat. Involym can be taken on an empty stomach or with food if it causes stomach upset.

There is no known harmful interaction between Isotroin (isotretinoin) and Zental (albendazole), so they are safe to take on the same day. However, to prevent any mild stomach upset and ensure optimal absorption, it is a good idea to space them out slightly. I suggest taking your Isotroin with a fat-containing evening meal, as it absorbs best with food, and taking your Zental a couple of hours later before sleep. If you have any concerns, your prescribing doctor is always there to help.

For active breakouts, generic topical azelaic acid or benzoyl peroxide can help reduce inflammation and clear pores. Azelaic acid is particularly wonderful because it also helps fade acne scars and dark spots. To rebuild skin texture from deeper scars, a prescription retinoid like tretinoin may be beneficial. I highly recommend discussing these gentle, effective alternatives with a dermatologist to find the perfect fit for your skin.

Eposoft (evening primrose oil) and antioxidant supplements are generally not known to cause significant weight gain, though some individuals may experience mild fluid retention. Stopping a short 10-day course of isotretinoin is also highly unlikely to trigger this. Since your diet hasn't changed, this sudden weight gain might be due to temporary water retention, stress, or minor metabolic fluctuations. I highly recommend discussing this with your doctor to check your thyroid levels or overall health just to be sure.