For severe cystic acne, a low dose of oral isotretinoin (10 mg) can take much longer to work, and sometimes a higher dose is needed to see significant improvement. Your topical clindamycin and benzoyl peroxide are excellent for surface bacteria, but deep cysts often need stronger internal treatment. Dark spots also take time to fade once the acne clears. I highly recommend discussing your progress with your dermatologist, as they can safely adjust your isotretinoin dose to help you get the clear skin you deserve.

It is completely normal to still experience acne breakouts two months into your Isotroin (isotretinoin) treatment. Many people experience a temporary flare-up or slow progress during the first eight to twelve weeks as the medicine works to clear deeper blockages. Please do not stop taking your medication, as consistency is key to seeing the best results, which usually become noticeable around the third or fourth month. I encourage you to keep your dermatologist updated on your progress so they can monitor your journey and reassure you.

Generally, combining oral isotretinoin (Isotroin) with topical tretinoin (found in Supatret C) is not recommended. Because both medications are strong retinoids, using them together can lead to severe skin dryness, redness, and irritation. While the topical antibiotics clindamycin and nadifloxacin (Nadoxin) are sometimes used, oral isotretinoin is incredibly effective on its own, and additional topicals are often unnecessary and can compromise your skin barrier. I highly recommend discussing this with your dermatologist to create a gentle, safe, and effective plan tailored just for you.

It is generally not recommended to use Zenderm BN cream while taking oral isotretinoin (Isotroin). Isotroin makes your skin very dry and sensitive. Zenderm BN contains a topical steroid, antibiotic, and antifungal. Applying a steroid to skin treated with isotretinoin can cause increased irritation, skin thinning, and can actually worsen acne. For your safety, it is best to use a gentle, fragrance-free moisturizer and consult your dermatologist before applying any medicated creams.

Eposoft (evening primrose oil) and antioxidant supplements are generally not known to cause significant weight gain, though some individuals may experience mild fluid retention. Stopping a short 10-day course of isotretinoin is also highly unlikely to trigger this. Since your diet hasn't changed, this sudden weight gain might be due to temporary water retention, stress, or minor metabolic fluctuations. I highly recommend discussing this with your doctor to check your thyroid levels or overall health just to be sure.

Yes, it is safe to take Isotroin 20mg instead of Isotane 20mg. Both of these are brand names for the exact same active generic medication, isotretinoin, at the same 20mg strength. Because they contain the same active ingredient, they work the same way in your body. You can safely make this switch, but I always recommend double-checking with your pharmacist or prescribing doctor.