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  5. My relative has had a severe skin infection for the last six months. Despite treating it with oral itraconazole and terbinafine, topical sertaconazole, and intravenous amikacin 500 mg, there has been no improvement. What alternative medications or treatment options should we consider?

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My relative has had a severe skin infection for the last six months. Despite treating it with oral itraconazole and terbinafine, topical sertaconazole, and intravenous amikacin 500 mg, there has been no improvement. What alternative medications or treatment options should we consider?

Asked by Male, 45 · 2 days ago

Since the infection has not responded to these standard treatments, the most important next step is to obtain a skin biopsy. This will allow for specialized cultures (fungal, bacterial, and mycobacterial) and drug-sensitivity testing to pinpoint the exact organism. Sometimes, chronic infections are caused by atypical bacteria or resistant fungi. Depending on the biopsy results, alternative medications may include advanced antifungals like voriconazole or posaconazole, or alternative antibiotics like clarithromycin or linezolid. I highly recommend consulting an infectious disease specialist or dermatologist to perform these diagnostic tests and safely guide the next steps of treatment.
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My relative has had a severe skin infection for the last six months. Despite treating it with oral itraconazole and terbinafine, topical sertaconazole, and intravenous amikacin 500 mg, there has been no improvement. What alternative medications or treatment options should we consider?

Answered 2 days ago