There is no single “most effective” tablet for alcoholism, as treatment depends on the individual’s health, drinking pattern, and readiness to quit; commonly prescribed medications include disulfiram, which causes unpleasant effects if alcohol is consumed, naltrexone, which reduces alcohol cravings, and acamprosate, which helps maintain abstinence, but all should be used under a doctor’s supervision along with counseling or behavioral therapy for the best results.