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  5. I was tested for HIV four months after a possible exposure (the partner?s HIV status was unknown, and the intercourse was protected with a condom). The test result was negative. It has now been six months since the possible exposure. Recently, I developed nasal blockage and breathing difficulty, so I visited a chest specialist who ordered a Total IgE test. The report showed highly elevated IgE levels (about 2000 kU/L). Should I be worried, and is there any relation between elevated IgE levels and HIV?

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I was tested for HIV four months after a possible exposure (the partner?s HIV status was unknown, and the intercourse was protected with a condom). The test result was negative. It has now been six months since the possible exposure. Recently, I developed nasal blockage and breathing difficulty, so I visited a chest specialist who ordered a Total IgE test. The report showed highly elevated IgE levels (about 2000 kU/L). Should I be worried, and is there any relation between elevated IgE levels and HIV?

Asked by Male, 30 · 2 months ago

Dr S Aneela

Dr S Aneela

M. Pharm (Pharmacology)., PhD

2 months ago

A negative HIV test done four months after a possible low-risk exposure (condom-protected intercourse) is highly reliable and indicates that you are not infected with HIV. Elevated Total IgE levels are not related to HIV infection and are usually associated with conditions such as severe allergies, asthma, or, less commonly, parasitic infections. Your nasal blockage and breathing difficulty are most likely due to an allergic cause. For reassurance, you may repeat the HIV test now and follow up with your chest specialist or an allergist/immunologist for further evaluation and treatment.
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Other Related topics like...

How reliable is a 4-month negative HIV test?Can elevated IgE levels cause breathing problems?Are nasal blockage and high IgE related?Should I see an allergist for high IgE?What treatments are available for high IgE levels?

  1. Causes of Nasal Blockage and Breathing Difficulty

    • Common causes include allergic rhinitis, sinusitis, nasal polyps, or structural issues like a deviated septum.
    • Consider consulting a healthcare provider for a thorough evaluation.

  2. Interpretation of Highly Elevated IgE Levels (~2000 kU/L)

    • Elevated IgE levels often indicate allergic conditions, such as asthma or atopic dermatitis.
    • It may also suggest parasitic infections or rare immune disorders like hyper-IgE syndrome.
    • Further evaluation by an allergist or immunologist is recommended.

  3. HIV Testing and Elevated IgE Levels

    • A negative HIV test four months post-exposure is generally reliable.
    • Elevated IgE levels are not directly correlated with HIV infection.

  4. Next Steps and Medical Advice

    • Consult a healthcare provider for a detailed history and physical examination.
    • Consider allergy testing and imaging for sinus evaluation if symptoms persist.

Answered 2 months ago

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