Yes, you can take these medicines, but they should not be taken at the exact same time. The active ingredients in the antacid and sucralfate can coat your stomach and bind to other medications, which significantly reduces the absorption and effectiveness of the chlordiazepoxide and clidinium bromide combination. To ensure all medications work properly, please space them out. Take the chlordiazepoxide and clidinium bromide at least 1 to 2 hours before or after taking the antacid or sucralfate. This simple adjustment prevents any interactions and helps manage your symptoms safely.