Since standard laxatives haven?t worked, you may have slow-transit constipation or pelvic floor dysfunction. I recommend consulting a gastroenterologist to discuss advanced prescription options like secretagogues (Linaclotide, Lubiprostone) or prokinetics (Prucalopride), which work differently than standard laxatives. If you want to explore non-allopathic options, Ayurvedic remedies like Triphala powder or Psyllium husk (Isabgol) with warm milk or water at bedtime can be highly effective. Daily probiotics and increasing dietary fibre and water intake are also crucial. Please consult a specialist for diagnostic tests like an anorectal manometry, to identify the exact cause before starting new medications.