High blood pressure is very common and highly manageable. To help protect your heart, doctors typically prescribe one or a combination of these main classes of generic medications: 1. ACE inhibitors (like lisinopril) or ARBs (like losartan): These help relax and widen your blood vessels. 2. Calcium channel blockers (like amlodipine): These relax the muscles of your blood vessels. 3. Diuretics or 'water pills' (like hydrochlorothiazide): These help your kidneys flush out excess sodium and water. 4. Beta-blockers (like metoprolol): These help your heart beat slower and with less force. Your doctor will find the best, safest option tailored specifically for your body.