Yes, you can generally use Lubrifresh Gel instead of Refresh Tears or Refresh Liquigel, as they all serve as lubricating drops to soothe dry, irritated eyes. However, please note that Lubrifresh Gel is a thicker formulation, which may cause temporary blurred vision immediately after use compared to the thinner Refresh Tears. Most importantly, these lubricants only soothe discomfort?they do not treat the underlying eye infection. You must continue using your prescribed infection medication as directed. Be sure to wait at least 10 to 15 minutes between applying your antibiotic drops and this lubricating gel so you do not wash the active medication out.