Persistent groin itching that does not respond to terbinafine or sertaconazole may indicate a resistant fungal strain, or a different condition altogether, such as contact dermatitis, eczema, or inverse psoriasis. For alternative pharmaceutical treatments, a doctor might consider oral itraconazole or a different topical antifungal like luliconazole. However, to find a permanent cure, it is essential to consult a dermatologist for a correct diagnosis, possibly via a skin scraping test. Meanwhile, keep the groin area completely clean and dry, wear loose cotton underwear, and avoid using over-the-counter steroid creams, which can worsen fungal infections. This condition is highly treatable once the exact cause is identified.