Generally, Folic Acid is taken daily throughout the first trimester (up to 12 weeks) to prevent birth defects, and is often continued longer. Lupigest 200 (progesterone) supports the uterine lining and is typically prescribed until the 12th week of pregnancy, though some cases require it for longer. However, the exact duration for both medications is highly personalised. It depends entirely on your wife's specific medical history and her ongoing clinical evaluations. Please ensure she takes these medicines exactly as directed by her obstetrician and does not stop them without direct medical advice.