Yes, Mahacef-200 Tablet (Cefixime) can generally be taken with Febrex Plus Tablet (Paracetamol, Phenylephrine, and Chlorpheniramine). Cefixime treats bacterial infections, while Febrex Plus helps reduce fever, relieve pain, and ease cold symptoms. However, it is always best to consult your healthcare provider to ensure there are no potential interactions or contraindications based on your specific health conditions.