Glutathione injections, along with vitamin C, are sometimes used for skin lightening, as they may reduce melanin production. Some people notice a brighter complexion within 4-8 weeks, but results vary. However, their effectiveness is not strongly proven, and long-term safety is uncertain. Possible risks include allergic reactions, skin rashes, digestive issues, and potential kidney or liver problems, especially with prolonged or unsupervised use. Because of these concerns, such treatments should only be taken under medical supervision.