Since Momoz-S (a potent steroid with salicylic acid) and Moisturex are not providing lasting relief, your symptoms suggest a resistant condition like palmoplantar psoriasis, chronic eczema, or a fungal infection. Prolonged steroid use without supervision can lead to skin thinning and rebound flare-ups. There is no single "best" medication without a definitive diagnosis. If it is psoriasis or severe keratoderma, a dermatologist may prescribe oral retinoids (like acitretin). If a fungal infection is suspected, topical or oral antifungals are required. Please consult a dermatologist for a physical exam or skin scraping to get a targeted, safe treatment plan. Meanwhile, keep your skin hydrated with plain petroleum jelly.