Yes, it is necessary to use all three medications as prescribed. Your symptoms suggest an allergic reaction combined with a bacterial infection, causing the swelling. Winolap is an antihistamine that treats your allergy symptoms, like watery eyes and a runny nose. Moxigram eye drops and Zymar ointment are both fluoroquinolone antibiotics. Using both ensures continuous, round-the-clock infection control. The drops are ideal for daytime use, while the ointment provides long-lasting treatment overnight. Skipping any of these can delay your recovery or worsen the infection. Ensure you space the eye drops at least 5 to 10 minutes apart, applying the ointment last.